- Classifier list
- Reference groups (Classifier 12.2)
- RMS (MYOD1)
- Name: Methylation class rhabdomyosarcoma (MYOD1)
- Description: The methylation class "rhabdomyosarcoma (MYOD1)" is based on tumours with the histological diagnosis of rhabdomyosarcoma that exhibit spindle cell or sclerosing features in most cases. Location is frequently the head and neck region; median age is 17 years (age range 4 to 59). Cases of this class carry a hotspot mutation in MYOD1. Copy number analysis shows frequent whole-chromosome losses, mostly involving chromosome 13q (80%) and losses on chromosome 10p (> 60%). The name given here is provisional.
- Histological diagnosis:
||Age [median (min-max)]
||NA (NA - NA)