Methylation class giant cell tumour of bone
- Name: Methylation class giant cell tumour of bone
- Description: The methylation class "giant cell tumour of bone" is based on tumours with the histological diagnosis of giant cell tumour of bone. Cases mostly arise in the epiphyseal-metaphyseal region of long tubular bones; median age is 29 years (age range 22 to 75). Cases of this class consistenly carry a H3F3A G34W/L hotspot mutation. Recurrent chromosomal alterations are not observed and most cases show a flat profile in copy number analysis.
- Histological diagnosis:
|Sample count||Ratio male/female||Age [median (min-max)]|
|9||NA||NA (NA - NA)|