- Classifier list
- Reference groups (Classifier 12.2)
- Name: Methylation class fibrous dysplasia
- Description: The methylation class "fibrous dysplasia" is based on tumours with the histological diagnosis of fibrous dysplasia, either in its monostotic or polyostotic form. Location is the skeleton, frequently a bone of the extremities; median age is 34 years (age range 15 to 61). Cases of this class consistenly carry a GNAS hotspot mutation at codon 201. Recurrent chromosomal alterations are not observed and most cases show a flat profile in copy number analysis.
- Histological diagnosis:
||Age [median (min-max)]
||NA (NA - NA)