- Classifier list
- Reference groups (Classifier 8.0)
- Name: Methylation class melanotic schwannoma
- Description: The methylation class "melanotic schwannoma" is based on tumors with the histological diagnosis melanotic schwannoma. Location is typically along the spinal meninges and frequently cervical; median age is 38 years (range 11 to 64). Numeric whole chromosome changes are frequent in this class, with gain of chromosome 5, 7 and 9 (> 50% of cases) and loss of chromosome 21 and 22 (>30%) being most frequent. Molecularly, theses tumors frequently carry mutations in PRKAR1A.
- Histological diagnosis:
||Age [median (min-max)]
||NA (NA - NA)